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1

Intracerebroventricular administration of CYX-6, a potent μ-opioid receptor agonist, a δ- and κ-opioid receptor antagonist and a biased ligand at μ, δ & κ-opioid receptors, evokes antinociception with minimal constipation and respiratory depression in rats in contrast to morphine

Imam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan, Cai, Yunxin, Qin, Yajuan, Li, Tingyou, Smith, Maree T.

Journal:

European Journal of Pharmacology

Year:

2020

Language:

english

File:

PDF, 6.71 MB

english, 2020

2

Orthogonal Lithography for Halide Perovskite Optoelectronic Nanodevices

Lin, Chun-Ho, Cheng, Bin, Li, TingYou, Retamal, Jose Ramon Duran, Wei, Tzu-Chiao, Fu, Hui-Chun, Fang, Xiaosheng, He, Jr-Hau

Journal:

Year:

2018

Language:

english

File:

PDF, 606 KB

english, 2018

3

ChemInform Abstract: A Highly dl-Stereoselective Pinacolization of Aromatic Aldehydes Mediated by TiCl4—Zn.

Tingyou Li, Wei Cui, Jigang Liu, Jianzhang Zhao, Zongmu Wang

Journal:

Year:

2000

File:

PDF, 30 KB

2000

4

Transformation of μ-opioid receptor agonists into biologically potent μ-opioid receptor antagonists

Tingyou Li, Yunden Jinsmaa, Masahiro Nedachi, Anna Miyazaki, Yuko Tsuda, Akihiro Ambo, Yusuke Sasaki, Sharon D. Bryant, Ewa Marczak, Qiang Li, H. Scott Swartzwelder, Lawrence H. Lazarus, Yoshio Okada

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 536 KB

english, 2007

5

Synthesis of 3,6-bis[H-Tyr/H-Dmt-NH(CH2)m,n]-2(1H)pyrazinone derivatives: Function of alkyl chain length on opioid activity

Kimitaka Shiotani, Tingyou Li, Anna Miyazaki, Yuko Tsuda, Sharon D. Bryant, Akihiro Ambo, Yusuke Sasaki, Lawrence H. Lazarus, Yoshio Okada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

6

Design and synthesis of opioidmimetics containing 2′,6′-dimethyl-l-tyrosine and a pyrazinone-ring platform

Kimitaka Shiotani, Tingyou Li, Anna Miyazaki, Yuko Tsuda, Toshio Yokoi, Akihiro Ambo, Yusuke Sasaki, Sharon D. Bryant, Lawrence H. Lazarus, Yoshio Okada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 135 KB

english, 2007

7

Application of liquid chromatography–tandem mass spectrometry for the determination of opioidmimetics in the brain dialysates from rats treated with opioidmimetics intraperitoneally

Kazuo Igarashi, Yuki Murabayashi, Koichiro Hotta, Youji Kitamura, Fumiyo Kasuya, Kimitaka Shiotani, Li Tingyou, Anna Miyazaki, Yuko Tsuda, Yoshio Okada, Shoji Fukushima

Journal:

Journal of Chromatography B

Year:

2004

Language:

english

File:

PDF, 98 KB

english, 2004

8

Immediate deamination from the aminomethyl group attached to 1,2-dihydropyrazin-2-one derivative during catalytic hydrogenation

Yoshio Okada, Yutaka Fujisawa, Akihisa Morishita, Kimitaka Shiotani, Anna Miyazaki, Yoshio Fujita, Tingyou Li, Yuko Tsuda, Toshio Yokoi, Sharon D. Bryant, Lawrence H. Lazarus

Journal:

Tetrahedron Letters

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

9

Studies on the structure–activity relationship of 2′,6′-dimethyl-l-tyrosine (Dmt) derivatives: bioactivity profile of H–Dmt–NH–CH3

Yoshio Fujita, Yuko Tsuda, Takashi Motoyama, Tingyou Li, Anna Miyazaki, Toshio Yokoi, Yusuke Sasaki, Akihiro Ambo, Hideko Niizuma, Yunden Jinsmaa, Sharon D. Bryant, Lawrence H. Lazarus, Yoshio Okada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

10

New series of potent δ-opioid antagonists containing the H-Dmt-Tic-NH-hexyl-NH-R motif

Tingyou Li, Kimitaka Shiotani, Anna Miyazaki, Yoshio Fujita, Yuko Tsuda, Akihiro Ambo, Yusuke Sasaki, Yunden Jinsmaa, Ewa Marczak, Sharon D. Bryant, Lawrence H. Lazarus, Yoshio Okada

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2005

Language:

english

File:

PDF, 116 KB

english, 2005

11

Structural studies of [2′,6′-dimethyl-l-tyrosine1]endomorphin-2 analogues: enhanced activity and cis orientation of the Dmt-Pro amide bond

Yoshio Okada, Yoshio Fujita, Takashi Motoyama, Yuko Tsuda, Toshio Yokoi, Tingyou Li, Yusuke Sasaki, Akihiro Ambo, Yunden Jinsmaa, Sharon D. Bryant, Lawrence H. Lazarus

Journal:

Bioorganic & Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 320 KB

english, 2003

12

Differentiation of opioid receptor preference by [Dmt1]endomorphin-2-mediated antinociception in the mouse

Yunden Jinsmaa, Yoshio Fujita, Kimitaka Shiotani, Anna Miyazaki, Tingyou Li, Yuko Tsuda, Yoshio Okada, Akihiro Ambo, Yusuke Sasaki, Sharon D. Bryant, Lawrence H. Lazarus

Journal:

European Journal of Pharmacology

Year:

2005

Language:

english

File:

PDF, 243 KB

english, 2005

13

Potent in vivo antinociception and opioid receptor preference of the novel analogue [Dmt1]endomorphin-1

Yunden Jinsmaa, Ewa Marczak, Yoshio Fujita, Kimitaka Shiotani, Anna Miyazaki, Tingyou Li, Yuko Tsuda, Akihiro Ambo, Yusuke Sasaki, Sharon D. Bryant, Yoshio Okada, Lawrence H. Lazarus

Journal:

Pharmacology Biochemistry and Behavior

Year:

2006

Language:

english

File:

PDF, 324 KB

english, 2006

14

Oral Bioavailability of a New Class of μ-Opioid Receptor Agonists Containing 3,6-Bis[Dmt-NH(CH2)n]-2(1H)-pyrazinone with Central-Mediated Analgesia

Jinsmaa, Yunden, Miyazaki, Anna, Fujita, Yoshio, Li, Tingyou, Fujisawa, Yutaka, Shiotani, Kimitaka, Tsuda, Yuko, Yokoi, Toshio, Ambo, Akihiro, Sasaki, Yusuke

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 268 KB

english, 2004

15

Genetic Analysis and Mapping of Genes Involved in Fertility of Pingxiang Dominant Genic Male Sterile Rice

Tingyou Huang, Yuping Wang, Bingtian Ma, Yuqing Ma, Shigui Li

Journal:

Journal of Genetics and Genomics

Year:

2007

Language:

english

File:

PDF, 774 KB

english, 2007

16

Development of Potent Bifunctional Endomorphin-2 Analogues with Mixed μ-/δ-Opioid Agonist and δ-Opioid Antagonist Properties

Fujita, Yoshio, Tsuda, Yuko, Li, Tingyou, Motoyama, Takashi, Takahashi, Motohiro, Shimizu, Yoshiro, Yokoi, Toshio, Sasaki, Yusuke, Ambo, Akihiro, Kita, Atsuko, Jinsmaa, Yunden, Bryant, Sharon D., Laza

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 171 KB

english, 2004

17

[Dmt1]DALDA analogues with enhanced μ opioid agonist potency and with a mixed μ/κ opioid activity profile

Bai, Longxiang, Li, Ziyuan, Chen, Jiajia, Chung, Nga N., Wilkes, Brian C., Li, Tingyou, Schiller, Peter W.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 580 KB

english, 2014

18

Endomorphin analogues with mixed μ-opioid (MOP) receptor agonism/δ-opioid (DOP) receptor antagonism and lacking β-arrestin2 recruitment activity

Cai, Jun, Song, Bowen, Cai, Yunxin, Ma, Yu, Lam, Ai-leen, Magiera, Julia, Sekar, Sunder, Wyse, Bruce D., Ambo, Akihiro, Sasaki, Yusuke, Lazarus, Lawrence H., Smith, Maree T., Li, Tingyou

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.32 MB

english, 2014

19

Development of Potent μ-Opioid Receptor Ligands Using Unique Tyrosine Analogues of Endomorphin-2

Li, Tingyou, Fujita, Yoshio, Tsuda, Yuko, Miyazaki, Anna, Ambo, Akihiro, Sasaki, Yusuke, Jinsmaa, Yunden, Bryant, Sharon D., Lazarus, Lawrence H., Okada, Yoshio

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 120 KB

english, 2005

20

Potent Dmt-Tic Pharmacophoric δ- and μ-Opioid Receptor Antagonists

Li, Tingyou, Fujita, Yoshio, Shiotani, Kimitaka, Miyazaki, Anna, Tsuda, Yuko, Ambo, Akihiro, Sasaki, Yusuke, Jinsmaa, Yunden, Marczak, Ewa, Bryant, Sharon D., Salvadori, Severo, Lazarus, Lawrence H.,

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 156 KB

english, 2005

21

Bifunctional [2‘,6‘-Dimethyl- l -tyrosine 1 ]endomorphin-2 Analogues Substituted at Position 3 with Alkylated Phenylalanine Derivatives Yield Potent Mixed μ-Agonist/δ-Antagonist and Dual μ-Agonist/δ-Agonist Opioid Ligands

Li, Tingyou, Shiotani, Kimitaka, Miyazaki, Anna, Tsuda, Yuko, Ambo, Akihiro, Sasaki, Yusuke, Jinsmaa, Yunden, Marczak, Ewa, Bryant, Sharon D., Lazarus, Lawrence H., Okada, Yoshio

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 169 KB

english, 2007

22

A highly dl-stereoselective pinacolization of aromatic aldehydes mediated by TiCl4–Zn

Li, Tingyou, Cui, Wei, Liu, Jigang, Zhao, Jianzhang, Wang, Zongmu

Journal:

Chemical Communications

Year:

2000

Language:

english

File:

PDF, 52 KB

english, 2000

23

[IEEE 2012 9th International Conference on Fuzzy Systems and Knowledge Discovery (FSKD) - Chongqing, Sichuan, China (2012.05.29-2012.05.31)] 2012 9th International Conference on Fuzzy Systems and Knowledge Discovery - The application of unified modeling language in the performance evaluation of R&D staff

Lan, Yazhu, Li, Tingyou

Year:

2012

Language:

english

File:

PDF, 228 KB

english, 2012

24

Organic certification and the market: organic exports from and imports to China

Xie, Biao, Tingyou, Li, Yi, Qian

Journal:

British Food Journal

Year:

2011

Language:

english

File:

PDF, 298 KB

english, 2011

25

Spectroscopic study on the photochromism of Schiff base N-salicylidene-α-methylbenzylamine

Zhao, Jianzhang, Zhao, Bing, Liu, Juzheng, Li, Tingyou, Xu, Weiqing

Journal:

Journal of Chemical Research

Year:

2000

Language:

english

File:

PDF, 40 KB

english, 2000

26

Impact of EU organic-certification regulation on organic exports from China

Biao, Xie, Tingyou, Li, Keqiang, Zhao, Yunguan, Xi

Journal:

Outlook on Agriculture

Year:

2005

Language:

english

File:

PDF, 62 KB

english, 2005

27

SPIE Proceedings [SPIE Geoinformatics 2008 and Joint conference on GIS and Built Environment: The Built Environment and its Dynamics - Guangzhou, China (Saturday 28 June 2008)] Geoinformatics 2008 and Joint Conference on GIS and Built Environment: The Built Environment and Its Dynamics - The coupling law of the interaction between economic development and eco-environment in medium-sized city: a case from Lianyungang city in China

Liu, Lin, Li, Tingyou, Lin, Zhenshan, Li, Xia, Liu, Kai, Xie, Biao, Zhang, Xinchang, Wang, Xinhao

Year:

2008

Language:

english

File:

PDF, 241 KB

english, 2008

28

[Dmt1]DALDA analogues modified with tyrosine analogues at position 1

Cai, Yunxin, Lu, Dandan, Chen, Zhen, Ding, Yi, Chung, Nga N., Li, Tingyou, Schiller, Peter W.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2016

Language:

english

File:

PDF, 323 KB

english, 2016

29

Enantioselective Synthesis of a Phenylalanine Library Containing Alkyl Groups on the Aromatic Moiety: Confirmation of Stereostructure by X-Ray Analysis

Li, Tingyou, Tsuda, Yuko, Minoura, Katsuhiko, In, Yasuko, Ishida, Toshimasa, Lazarus, Lawrence H., Okada, Yoshio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2006

Language:

english

File:

PDF, 164 KB

english, 2006

30

Studies on the Mechanism of 1,2-Dihydropyrazin-2-one Ring Formation from Dipeptidyl Chloromethyl Ketone and Its Chemical Properties: Immediate Deamination during Catalytic Hydrogenation

Miyazaki, Anna, Fujisawa, Yutaka, Shiotani, Kimitaka, Fujita, Yoshio, Li, Tingyou, Tsuda, Yuko, Yokoi, Toshio, Bryant, Sharon D., Lazarus, Lawrence H., Okada, Yoshio

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Year:

2005

Language:

english

File:

PDF, 206 KB

english, 2005

31

Synthesis and biological evaluation of fentanyl analogues modified at phenyl groups with alkyls

Qin, Yajuan, Ni, Luofan, Shi, Jiawei, Zhu, Zhiying, Shi, Saijian, Lam, Ai Leen, Magiera, Julia, Sekar, Sunderajhan, Kuo, Andy, Smith, Maree T., Li, Tingyou

Journal:

ACS Chemical Neuroscience

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

32

Nonlinear relationship of vegetation greening with nature and human factors and its forecast – A case study of Southwest China

Liu, Huiyu, Jiao, Fusheng, Yin, Jingqiu, Li, Tingyou, Gong, Haibo, Wang, Zhaoyue, Lin, Zhenshan

Journal:

Ecological Indicators

Year:

2020

File:

PDF, 4.57 MB

2020

33

Effects of melatonin-treated Nasturtium officinale on the growth and cadmium accumulation of subsequently grown rice seedlings

Shi, Jun, Xiang, Zufen, Peng, Tao, Li, Hongyan, Huang, Kewen, Liu, Dingyou, Huang, Tingyou

Journal:

International Journal of Environmental & Analytical Chemistry

Year:

2020

File:

PDF, 965 KB

2020

34

Novel Âµ opioid antagonists derived from the Âµ opioid agonists endomorphin and [Dmt 1 ]DALDA (HâDmtâDâArgâPheâLysâNH 2 )

Shi, Saijian, Xu, Jian, Feng, LingLing, Fan, Xin, Chen, Zhen, Qin, Yajuan, Chung, Nga N., Li, Tingyou, Schiller, Peter W.

Journal:

Chemical Biology & Drug Design

Year:

2020

File:

PDF, 9.17 MB

2020

35

Applicability of the adjusted graded prognostic assessment for lung cancer with brain metastases using molecular markers (LungâmolGPA) in a Chinese cohort: A retrospective study of multiple institutions

Zhang, Tingyou, Zhang, Yu, Zhou, Lin, Deng, Shanshan, Huang, Meijuan, Liu, Yuncong, Liu, Yongmei, Gong, Youlin, Zhu, Jiang, Xue, Jianxin, Bai, Yuju, Ma, Hu, Zhang, Yan, Yu, Min, Li, Yanying, Wang, Yon

Journal:

Cancer Medicine

Year:

2020

File:

PDF, 441 KB

2020